I have 1 set of primordials. I found using navigator, DM, GPD and prisoner works, a little slow on manual but gets the job done. Just use GPD to keep immunity going and corrupt the main with Nav or prisoner. I use immunity on GPD and DM to keep from corruption at the start. I use chance and steel on Nav.
I tried G cotd and found her a little weak, prisoner is as little stronger and can corrupt and stun. I didn't try AoM, revive skill may come in handy. Immunity talis helps a lot from getting corrupted or stunned on the first round.
Without primordials you need to get immunity, the chance of immunity from primordials is a good backup. Just corrupt the main and wear them down. GPD great for heal as well.