Perfect Corruption is the only reliable way I've found for dealing with enemies using Destiny talismans. Since the AI always seems to generate invincibility when hit (even by attacks that remove buffs) the only way I can effectively counter Destinies is by preventing buffs altogether. I was fortunate enough to pull Benjamin Breeg Eddie almost as soon as I returned to the game and his Present power ability both removes immunity/perfect immunity and applies perfect corruption, making him perfect for fighting those awful infinite-buff-stackers. I know Fear of the Dark Eddie can also apply perfect corruption, but I can't remember anyone else.