FYI..... I was using the new REAPER talis on the new Angel of Death in the gauntlet and skull quests, and the passive "and will remove all beneficial effects and inflict Perfect Bleed on a random enemy every turn" seemed to not apply on the very first turn. It only worked every turn after. Which isn't really every turn then, is it? Not sure if it's a bug or what. I could report it, but I'm sooooo tired of sending NF emails.
In this image, no one has attacked yet. First turn and no random enemy has perf. bleed, they all still have their buffs.