I guess when you say Assassin Bat, you mean Angel of Death? Don't have this one, unfortunately.

My current set-up, on my 7th playthrough right now is this:

Eddie: Gambler, Labyrinth+T3 3* talisman which gives def+mres

Toons, in this order:
Raven witch: Reaper, random purple, t2 2* talisman attack+magic
Beast: Reaper+2 other
Wrath: Reaper+2other, but changed it to eclipse to test it out.

I might lose once or twice on the 2 hour run.

I would try your setup, but I am missing the other talismans