I I am using the following
KP. warlord/sustain/sacred
Gambler. Cosmic/warlord. Have tried various 3 set purple no real difference
Major. Singularity
Charlotte. Dominance/sacred,/cosmic
I've no problems on madness, can do insanity 95% success.
You may try some other toon that can use singularity or alchemy to replace major. I heard some success with the quantum talisman, maybe on raven or some other healer.
I found orbit or valor on Charlotte not as reliable.