I've been doing ok-ish with grinding on A Matter of Life and Death (Battlefield, Hard) for 1-star red evo runes, and I get some 2-star red evo runes in the process. It's been taking a few days of grinding, though, just to get the 6 1-star red evo runes needed to upgrade a 3-star talisman to 4-star.

Of course I end up getting a Samurai Eddie from a regular rare soul...Given the amount of Ironite I have stockpiled, I wouldn't mind seeing talisman upgrade kits in the store.