Does anyone know? Did devs say anything about this?
I leveled the Vampiric Talisman set for my Corrupted Harpy knowing that it wouldn't work with her, but still, it's an amazing set that I'd love to use on the assassin Children of the Damned if I ever get him.
Although, why does it only work with physical attacks? Assassins are by far the most squishy class and the only assassin that I can recall that deals physical damage alone is the undead soldier. Why would you make a talisman set for them if only one, or a few, can actually benefit from it?