The one exception is listed in some skills is that damage will scale with stats that are not attack or magic. For example Cyborg Eddie’s attacks scake with the special stat, and is listed in the skill “damage scales with special “. So for a character like that you would want to boost their special stat. fear of the dark eddie’s damage scales with defense so you would not want to choose talismans that boost MR instead of defense if you are trying to increase damage output, unless it was one that boosted both MR and defense